5% off your first order when you Sign up
  • Code: GET20 for 20% off Ancient + Brave
  • Free delivery on all orders over £15
  • Free tote bag with your Avene orders
£67.49

Life Extension SAMe S-Adenosyl-Methionine 400mg Tablets 60

Life Extension SAMe S-Adenosyl-Methionine 400mg Tablets 60

Life Extension SAMe S-Adenosyl-Methionine 400mg Tablets - 60

Mood balance | Liver detox support | Joint mobility

  • Helps maintain stable mood and emotional wellbeing
  • Promotes healthy liver function and detoxification
  • Supports joint flexibility and connective tissue health
  • Encourages neurotransmitter and antioxidant synthesis
  • Vegetarian and non-GMO formulation
Description

Life Extension SAMe S-Adenosyl-Methionine 400mg Tablets

Life Extension SAMe (S-Adenosyl-Methionine) 400mg Tablets deliver a potent dose of this naturally occurring compound to support mood balance, joint comfort, and liver health. SAMe plays a crucial role in methylation, neurotransmitter synthesis, and glutathione production, helping maintain optimal cellular function and overall wellbeing. This vegetarian and non-GMO formula is ideal for those seeking comprehensive support for both mind and body vitality.

Key Benefits of Life Extension SAMe 400mg

  • Helps maintain stable and balanced mood
  • Promotes healthy liver function and detoxification
  • Supports joint mobility and connective tissue health
  • Encourages neurotransmitter synthesis for cognitive support
  • Enhances glutathione activity for antioxidant protection
  • Suitable for vegetarians and non-GMO

How Does Life Extension SAMe Support the Body?

SAMe (S-Adenosyl-Methionine) is an amino acid derivative found in the body, particularly in the liver and brain, where it contributes to several key biochemical processes. It functions as a methyl donor, supporting the activation of essential molecules and the synthesis of polyamines for cell growth, neuronal regeneration, and gene expression. SAMe also plays a vital role in trans-sulphuration — a process that produces cysteine and glutathione, crucial for antioxidant defence.

SAMe, Mood & Cognitive Function

SAMe contributes to the synthesis of neurotransmitters such as serotonin, dopamine, and norepinephrine, all of which are essential for mood regulation and cognitive performance. By supporting acetylcholine production, SAMe may also help maintain mental clarity and protect against age-related cognitive decline. Studies suggest that maintaining adequate SAMe levels can assist in promoting a stable mood without common side effects associated with other interventions.

SAMe for Joint & Liver Health

As we age, SAMe levels can decline, impacting joint flexibility and liver function. Supplementation helps replenish these levels, aiding in the maintenance of healthy cartilage and supporting the liver’s detoxification processes. SAMe also assists in glutathione regeneration — a critical antioxidant that helps protect the liver from oxidative stress and supports overall metabolic balance.

How to Use

Take one (1) tablet one to three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner. For optimal results, take with co-factors including vitamins B12, B6, and folic acid.

Key Ingredients in Life Extension SAMe 400mg

  • S-Adenosyl-Methionine (SAMe) – Supports methylation, neurotransmitter balance, joint health, and liver detoxification
  • Vitamin B6, B12 & Folic Acid (recommended co-factors) – Enhance SAMe activity and methylation efficiency
  • Cellulose & Plant-based Coating – Suitable for vegetarians, ensuring stability and absorption

FAQs

What is SAMe used for?
SAMe supports emotional wellbeing, joint comfort, and liver detoxification by assisting in key cellular and metabolic processes.

Can SAMe support mood and cognitive function?
Yes, SAMe contributes to the production of neurotransmitters like serotonin and dopamine, promoting a stable mood and mental clarity.

Is SAMe suitable for vegetarians?
Yes, this formula is vegetarian-friendly and non-GMO, suitable for a wide range of dietary preferences.

When should I take SAMe?
It’s best taken on an empty stomach for maximum absorption, ideally with B-vitamin co-factors such as B6, B12, and folic acid.

Ingredients
  • Serving Size 1 enteric coated vegetarian tablet

    Amount Per Serving

    S-Adenosyl-Methionine

    400 mg

    Other ingredients: cellulose, methacrylic acid copolymer, mannitol, citric acid, titanium dioxide, stearic acid, silica, hydroxypropyl methylcellulose, glyceryl triacetate, sodium starch glycolate, croscarmellose sodium, yellow ochre.

    Non-GMO

    Dosage and Use
    • Take one (1) tablet one to three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner..
    • Take with co-factors vitamins B12, B6, and folic acid.
    Caution

    SAMe should not be taken by those diagnosed with bipolar disorder.

Important info
  • Disclaimer: This product is not intended to diagnose, treat, cure, or prevent any disease or health condition. Results may vary from individual to individual. While we try to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Please check the bottle for the most up to date information.
  • Type: Tablet
  • Free from: Gluten
  • Gender: Unisex
  • Suitable for: Vegetarian
  • Age Range: 15-35, 36-49, Over 50
  • Landys Chemist is committed to creating a more sustainable world. As part of our commitment we only use recyclable materials for our packaging. That means no plastic waste and we're alway looking for ways to improve further. In addition we recycle the vast majority of our own waste. We also provide invoices electronically rather than on paper to reduce paper waste.
  • As an NHS business we work tirelessly to provide support to our local community with a particular focus on those most vulnerable and in need. In addition we also support a number of local charities in North West London to try and help create a more equitable society.

In stock
Earn 67 points. Learn more.

Leave a review

Ask a Question

Find Life Extension SAMe S-Adenosyl-Methionine 400mg Tablets 60 in these ranges: